Hi Guys(probably only me :P),
This article was discussed in our group and worth mentioning a short review here. Just to start with if CVNH means Cyanovirin-N homolog proteins which are not very well studied. Here author talks about different types of CVNH and differentiate these on functional/structural basis. Here is type III domains of CVNH:
Both of the domains CVNH and LysM has been shown here to be Carbohydrate specific. Similarity between CVNH and LysM domain has been shown to argue for the similar function.
Further they have determined 3D NMR structure of this construct(MoCVNH-LysM).
This article was discussed in our group and worth mentioning a short review here. Just to start with if CVNH means Cyanovirin-N homolog proteins which are not very well studied. Here author talks about different types of CVNH and differentiate these on functional/structural basis. Here is type III domains of CVNH:
Both of the domains CVNH and LysM has been shown here to be Carbohydrate specific. Similarity between CVNH and LysM domain has been shown to argue for the similar function.
Further they have determined 3D NMR structure of this construct(MoCVNH-LysM).
That
is all except more explanation on carbohydrate binding and for more details you
can always refer to article.
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